NAD+
ALASKA

Nicotinamide Adenine Dinucleotide (NAD+) is a naturally occurring coenzyme found in your cells and plays a critical role in cellular metabolism and energy homeostasis. As we age, our NAD+ levels drop, but with new therapies available, we can help to restore it.

THE SCIENCE

Nicotinamide adenine dinucleotide (NAD+) is an essential pyridine nucleotide that serves as an essential cofactor and substrate for a number of critical cellular processes involved in oxidative phosphorylation and ATP production, DNA repair, epigenetically modulated gene expression, intracellular calcium signaling, and immunological functions.

DNA damage due to free radical or ultraviolet attack, resulting in significant poly(ADP-ribose) polymerase (PARP) activation and a high turnover and subsequent depletion of NAD+, and/or chronic immune activation and inflammatory cytokine production resulting in accelerated CD38 activity and decline in NAD+ levels.

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